Often used for:
Brain tumors, Germ cell tumors, Hepatoblastoma, Osteosarcoma, Adrenocortical tumors, Other solid tumors
About cisplatin
Cisplatin is a type of chemotherapy known as a platinum analog. It slows or stops the growth of cells and is usually used in combination with other medicines. Patients will have regular blood tests to monitor blood counts, kidney and liver function, and electrolytes, and may have hearing tests throughout treatment.
Possible late effects
- Fertility problems
- Delayed puberty
- Secondary cancers
- Peripheral neuropathy
- Kidney problems
Possible side effects
- Nausea and vomiting
- Low blood counts after 14–21 days (may increase the risk of infection, bleeding, anemia, and/or fatigue)
- Loss of appetite
- Diarrhea
- Hair loss
- Loss in the ability to taste food or changes in taste
- Dehydration
- Ringing in the ears
- Hearing loss
- Skin irritation at the IV site
- Kidney problems
- Numbness or tingling of the hands or feet
- Low levels of magnesium, potassium, calcium, sodium, or phosphorus in the blood
- Change in the normal menstrual cycle
- Infertility
- Not all patients who take cisplatin will experience these side effects. Please report all suspected side effects to your doctor or pharmacist.
Tips for families
- Discuss all questions and instructions with your doctor or pharmacist.
- Medicines will be prescribed to reduce nausea and vomiting during and after treatment.
- Patients may receive IV fluids before and after cisplatin; report decreased urination to the care team.
- The doctor may prescribe magnesium, potassium, calcium, or phosphorus supplements or add them to IV fluids.
- Watch for signs of hearing loss and attend recommended hearing tests.
- Sexually active patients should prevent pregnancy during treatment and for 6 months after therapy.
- Inform the doctor if the patient is pregnant or breastfeeding.
- Tell the care team about pre-existing hearing problems or poor kidney function.
- Caregivers should avoid contact with patient body fluids for 48 hours after treatment and follow safe handling instructions.
