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What is Factor IX concentrate?

Factor IX concentrate replaces clotting factor IX to manage bleeding disorders. It comes as a powder to be mixed with sterile water and given by IV.

Possible side effects

  • Allergic reactions (itching, hives, swelling, tightness in throat, trouble breathing)
  • Fever or chills
  • Bluish skin coloration
  • Chest pain or shortness of breath
  • Cough or taste changes
  • Headache
  • Diarrhea, vomiting, or nausea
  • Dizziness
  • Lower leg pain
  • Unusual bleeding, bruising, or weakness
  • Injection-site redness, pain, swelling, itching, rash
  • Numbness or weakness in limbs or one side of the body
  • Symptoms of allergic reaction also include rash, hives, itching, chills, fever, headache, muscle ache, shortness of breath, coughing, tightness in throat, swelling of face or neck
  • Not all patients will experience these side effects. Report any symptoms to the care team.

Tips for patients and families

  • Discuss all questions with your doctor or pharmacist.
  • Store in the refrigerator; do not freeze. May be kept at room temperature for up to 6 months (record the date).
  • Do not use past the expiration date.
  • Ensure you understand home infusion instructions before self-administration.
  • Have another trained person available; contact the care team for missed dose guidance.
  • Warm powder and diluent to room temperature before mixing; use within 3 hours of reconstitution.
  • Use new needles/syringes each time and dispose of sharps safely.
  • Consult the care team about disposal of leftover medicine and supplies.