Often used for:
Hepatocellular carcinoma, renal cell carcinoma, thyroid cancer, acute myeloid leukemia
About sorafenib
Sorafenib is a tyrosine kinase and VEGF inhibitor that blocks tumor cell signals and angiogenesis. Patients undergo regular lab tests to monitor blood counts and organ function.
Sorafenib at home
- Take at the same time each day on an empty stomach (1 hour before or 2 hours after eating).
- Swallow tablets whole; they may be dissolved in water if needed.
- Store at room temperature.
- If a dose is missed, skip it and resume the regular schedule. Do not double doses.
- Do not use past the expiration date.
Possible side effects
- Hand-foot syndrome (tingling, redness, and flaking skin)
- Rash, itching, or dry skin
- Diarrhea
- Fatigue or weakness
- High blood pressure
- Low blood counts
- Numbness or tingling
- Nausea or vomiting
- Loss of appetite and weight loss
- Shortness of breath
- Joint or muscle pain
- Constipation
- Mouth sores
- Hair loss
- Slow wound healing
- Liver problems
- Not all patients experience these effects. Report all symptoms.
Tips for families
- Discuss all recommendations with the care team.
- Drink plenty of fluids as directed.
- Use birth control during treatment and for 6 months after therapy.
- Inform the doctor if pregnant or breastfeeding.
- Report new medicines to the care team to monitor for interactions.
- Follow instructions for safe handling and disposal.
